Side effects of commonly used medications in horses and ponies Optim Equine Camilla Whishaw

Side effects of commonly used medications in horses and ponies

The judicious use of many medications in our horses and ponies can be important and even life saving in some situations, yet they are not without their side effects. Some of the most commonly used medications can have the greatest impact on the long term health of our horses and ponies.

Corticosteroids (such as prednisolone and dexamethasone), non-steroidal anti-inflammatory drugs (such as phenylbutazone, firocoxib, flunixin), gastric ulcer medications and antibiotics all impact gastrointestinal (GI) ‘gut’ health through several different mechanisms. These may include: irritating the sensitive tissue which lines the digestive tracts of our horses and ponies, potentially causing gastric ulceration and/or bleeding; causing GI dysbiosis (adversely impacting the delicate microflora populations within our horses’ and ponies’ GI tracts); and altering nutrient absorption and metabolism (the way our horses and ponies digest, utilise and excrete nutrients). 

Good gut health is central to the overall health and wellbeing in our horses. We know that beyond digestive health, gut health in our horses and ponies significantly influences: immune health; bone, cartilage and joint health; respiratory/airway health; metabolic health; reproductive health/fertility; hoof health; laminitis risk; and even behaviour and motor patterns in our horses.

These are just some of the reasons why it is important to use any medications judiciously- even ones that are routinely employed in many situations. In the case that these medications are required, strategic nutritional supplementation and in many cases, appropriately prescribed herbal medicines can help to address some of the nutrient depletions and side effects caused by these medications. Additionally they can help to return the digestive system to the best possible state of health.

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